| AASLD 
                          Liver Meeting Starts Today in Boston
 
 
                          
                           
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                                  | SUMMARY: 
                                    The 
                                    60th Annual Meeting of the American Association 
                                    for the Study of Liver Diseases (AASLD) -- 
                                    better known as "The 
                                    Liver Meeting" -- gets underway Friday, 
                                    October 30, and will run through November 
                                    1 at the Hynes Convention Center in Boston. 
                                    Treatments for hepatitis B and C will feature 
                                    prominently in the conference program. |  |  |  |   
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  The 
                        Liver Meeting covers all aspects of liver disease, but 
                        a significant proportion of the nearly 2000 abstracts 
                        to be presented are devoted to treatment and management 
                        of patients with viral hepatitis. Approximately 
                          10% of Americans have some form of liver disease, according 
                          to the conference organizers. Liver cancer is one of 
                          the few cancers growing in incidence, and the ongoing 
                          obesity epidemic "has dire consequences for the 
                          nation's liver health and wellness." Several 
                          pharmaceutical companies have already announced some 
                          of the new data to be presented on their experimental 
                          therapies: Bristol-Myers 
                          Squibb: data on 4 compounds including approved anti-HBV 
                          drug entecavir 
                          (Baraclude), experimental HCV protease inhibitor 
                          BMS-650032, pegylated interferon lambda, and investigational 
                          compound brivanib for treatment of hepatocellular carcinoma.
 GlobeImmune: late-breaker presentation on GI-5005 
                          therapeutic HCV vaccine.
 
 Idera Pharmaceuticals: data on DNA-based toll-like 
                          receptor 9 (TLR9) agonist IM0-2125 
                          for HCV treatment.
 
 Roche: data from a study of the experimental 
                          HCV protease inhibitor RG7227 
                          (ITMN-191) plus an HCV polymerase inhibitor.
 
 Schering-Plough: data on investigational HCV 
                          protease inhibitor boceprevir 
                          (including SPRINT-1 results) and next-generation HCV 
                          protease inhibitor narlaprevir (SCH 900518), as well 
                          as studies of pegylated 
                          interferon alfa-2b (PegIntron).
 Scynexis: 
                          Phase 1b data on novel anti-HCV agent SCY-635.
 Vertex: sustained virological response (SVR) 
                          data Study C208 and final PROVE-3 results on investigational 
                          HCV protease inhibitor telaprevir.
 For 
                          further information about the Liver Meeting program, 
                          see www.aasld.org/thelivermeeting. 10/30/09 Sources American 
                          Association for the Study of Liver Diseases.  Bristol-Myers 
                          Squibb. New Data on Four Bristol-Myers Squibb Compounds 
                          to Be Presented at AASLD 2009. Press release. October 
                          1, 2009. Bristol-Myers 
                          Squibb and ZymoGenetics. Bristol-Myers Squibb and ZymoGenetics 
                          to Present Final Phase Ib Data on PEG-Interferon Lambda 
                          at AASLD 2009. Press release. October 1, 2009. GlobeImmune. 
                          GlobeImmune Announces Late-Breaker Presentation of GI-5005 
                          Treatment Response Data at AASLD 2009 Meeting. Press 
                          release. October 6, 2009. Schering-Plough 
                          . Schering-Plough Highlights Boceprevir, Narlaprevir 
                          (SCH 900518) and PegIntron Data at the American Association 
                          for the Study of Liver Diseases (AASLD) 2009 Annual 
                          Meeting. Press release. October 15, 2009.
 Vertex. Vertex Pharmaceuticals Announces Publication 
                          of Telaprevir Abstracts for Presentation at the 60th 
                          AASLD Meeting. Press release. September 24, 2009.
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